PeptideTDB

Effects of fish protein hydrolysate ingestion on endothelial function compared to whey protein hydrolysate in humans

Oliveira GV, Volino-Souza M, Cordeiro EM, Conte-Junior CA, Alvares TS. Int J Food Sci Nutr. 2020; 71(2):242–248.

PubMed 31271072 · doi:10.1080/09637486.2019.1635090

Human trial (controlled)Blood pressure & vesselsFish protein hydrolysateOral

Compares people who got the treatment with people who did not.

Who or what was studied
9 healthy adults
Design
Single-dose comparison of fish protein hydrolysate, whey protein hydrolysate and placebo
Dose
20 g, one dose
Duration
Measured up to 120 minutes after the dose

What it found

Whey protein hydrolysate increased endothelium-dependent dilation of a blood vessel 30 minutes after the dose compared with placebo. Fish protein hydrolysate did not. In a lab assay the fish product had higher total antioxidant capacity than the whey product.

What it doesn't show

Nine people and a single dose, so it says nothing about longer-term use or blood pressure. It tested a general fish hydrolysate, not a defined peptide.

Funding and conflicts of interest

No funding or conflict-of-interest statement appears in the PubMed record. Check the full text.

Summary written from the study's abstract and checked against PubMed on November 9, 2026. How we check studies. Educational information, not medical advice.

Related studies