PeptideTDB

Therapeutic effects of marine collagen peptides on Chinese patients with type 2 diabetes mellitus and primary hypertension

Zhu CF, Li GZ, Peng HB, Zhang F, Chen Y, Li Y. Am J Med Sci. 2010; 340(5):360–366.

PubMed 20739874 · doi:10.1097/MAJ.0b013e3181edfcf2

Human trial (controlled)Blood pressure & vesselsMarine (fish-derived) collagen peptidesOral

Compares people who got the treatment with people who did not.

Who or what was studied
100 patients with type 2 diabetes and primary hypertension (50 per group) plus 50 healthy comparison subjects, in China
Design
Randomised, double-blind; patients also kept taking their regular diabetes and blood-pressure medicines
Dose
Marine collagen peptides from deep-sea fish, twice daily; dose not given in the abstract
Duration
3 months

What it found

Compared with patient controls, the marine collagen peptide group had lower fasting blood glucose, HbA1c, diastolic blood pressure, mean arterial pressure, triglycerides, total and LDL cholesterol and creatinine, and higher HDL cholesterol and insulin sensitivity.

What it doesn't show

Patients stayed on their regular medicines, so this is an add-on effect in people with diabetes and hypertension, not in healthy people. The abstract reports lower diastolic and mean arterial pressure but does not list systolic pressure among the significant results, and it gives no dose.

Funding and conflicts of interest

No funding or conflict-of-interest statement appears in the PubMed record. Check the full text.

Summary written from the study's abstract and checked against PubMed on November 9, 2026. How we check studies. Educational information, not medical advice.

Related studies