GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
Pickart L, Vasquez-Soltero JM, Margolina A. Biomed Res Int. 2015; 2015:648108.
PubMed 26236730 · PMC4508379 · doi:10.1155/2015/648108
Summarises other people's work. Generates no new data.
- Who or what was studied
- Review of research on GHK, a peptide found in human plasma that declines with age
- Design
- Narrative review
What it found
Describes GHK, bound to copper, as supporting wound healing and skin repair, mainly from animal and cell work, and reports that cosmetic products containing it were found to improve skin firmness, elasticity and fine lines. It also reports that GHK can raise or lower the activity of thousands of genes.
What it doesn't show
A review, not a trial: the abstract gives no sample sizes for the cosmetic findings, and a gene-expression result is not a clinical outcome. Read the paper's own disclosures for any commercial ties.
Funding and conflicts of interest
No funding or conflict-of-interest statement appears in the PubMed record. Check the full text.
Summary written from the study's abstract and checked against PubMed on November 9, 2026. How we check studies. Educational information, not medical advice.
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